SKRIPSI

Penetapan Kadar Air dan Abu serta Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kedabu (Sonneratia ovata Backer)

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Tumbuhan kedabu (Sonneratia ovata Backer) merupakan salah satu spesies Sonneratia yang digunakan masyarakat sebagai tanaman obat tradisional. Ekstrak etanol daun kedabu (Sonneratia ovata Backer) mengandung senyawa metabolit sekunder golongan fenolik, flavonoid, alkaloid dan steroid yang diketahui dapat menghambat aktivitas antibakteri. Salah satu persyaratan mutu ekstrak adalah penentuan kadar air dan kadar abu. Penelitian ini bertujuan untuk menentukan kadar air dan kadar serta mengetahui adanya aktivitas antibakteri ekstrak etanol daun kedabu (Sonneratia ovata Backer) terhadap bakteri Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus dan Bacillus subtilis. Kadar air ekstrak etanol daun kedabu (Sonneratia ovata Backer) sebesar 10,8602%, serta kadar abu ekstrak etanol daun kedabu (Sonneratia ovata Backer) sebesar 3,3714%. kadar air ekstrak etanol daun kedabu (Sonneratia ovata Backer) tidak memenuhi persyaratan sedangkan hasil kadar abu memenuhi persyaratan ekstrak sebagai bahan obat yang telah ditetapkan. Uji aktivitas antibakteri ekstrak etanol daun kedabu (Sonneratia ovata Backer) pada konsentarsi ekstrak 20%; 40%; 60% dan 80% memiliki aktivitas dalam menghambat pertumbuhan bakteri Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus dan Bacillus subtilis.

ABSTRACT
Kedabu plant (Sonneratia ovata Backer) is one of the Sonneratia species used by the community as a traditional medicinal plant. Kedabu (Sonneratia ovata Backer) leaf ethanol extract contains secondary metabolites of phenolic groups, flavonoids, alkaloids and steroids known to inhibit antibacterial activity. One of the extract quality requirements is the determination of the water content and the ash content. This study aims to determine the water content and content and to determine the antibacterial activity of Kedabu (Sonneratia ovata Backer) leaf ethanolic extract against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis bacteria. The water content of the ethanolic extract of kedabu (Sonneratia ovata Backer) leaf was 10.8602% and the ash content of the ethanolic extract of kedabu (Sonneratia ovata Backer) leaf was 3.3714%. The water content of the ethanolic extract from the leaves of kedabu (Sonneratia ovata Backer) did not meet the requirements, while the ash content results met the requirements of the extract as a prescribed medicinal ingredient. Test for antibacterial activity of ethanol extract from Kedabu leaves (Sonneratia ovata Backer) at an extract concentration of 20%; 40%; 60% and 80% inhibit the growth of the bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis.

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Ketersediaan

Informasi Detail

Judul Seri

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No. Panggil

CDS1328

Penerbit

Pekanbaru : S1 Farmasi STIFAR Riau., 2022

Deskripsi Fisik

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Bahasa

Indonesia

ISBN/ISSN

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Klasifikasi

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Tipe Isi

text

Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

DAUN KEDABU

Info Detail Spesifik

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Pernyataan Tanggungjawab

Penulis,Desi Setia Wati ; Pembimbing1,Emma Susanti ; Pembimbing2,Neni Frimayanti

Versi lain/terkait

Lampiran Berkas

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